Related Events

BME Seminar Series – W. Mark Saltzman

Safe Synthetic Particles that Function Like Viruses

Chair, Department of Biomedical Engineering
Yale University

Tuesday, November 2, 2010
44 Cummington St.
Room 203 at 4:00
(refreshments at 3:45)

Viruses are famous for their ability to target specific cell populations in the body and deposit their genetic materials within these cells.  There have been major efforts to use viruses as delivery vehicles for genes and drugs, but administration of viruses or modified viruses has serious drawbacks, including the potential for stimulating unwanted immune reactions and serious side effects. Here, we pursue an alternate approach: using building virus properties into synthetic polymer particles, particularly those formed from hydrophobic degradable polymers. These synthetic particles are endowed with characteristics of viruses, giving them properties that make them useful vehicles for drug and oligonucleotide delivery while still being safe. The application of these synthetic particles will be illustrated in the treatment of cancer and infectious diseases.


W. Mark Saltzman’s research interests include drug delivery to the brain, materials for vaccine delivery, and tissue engineering; he has published over 200 research papers, 3 books, 2 edited books, and 15 patents in these fields.  He graduated with distinction from Iowa State University, in 1981with a B.S. in chemical engineering and pursued graduate studies at the Massachusetts Institute of Technology, where he earned an M.S. in chemical engineering in 1984 and a Ph.D. in medical engineering in 1987. He joined the faculty at Johns Hopkins University in 1987 as assistant professor of chemical engineering; he was promoted to associate professor in 1992 and professor in 1995.  In 1996, he became professor of chemical engineering at Cornell University and, in 2001, he was named the first holder of the BP Amoco/H. Laurance Fuller Chair in Chemical Engineering. He moved to Yale University as the Goizueta Foundation Professor of Chemical and Biomedical Engineering in July of 2002 and, in 2003, he became the first chair of the Department of Biomedical Engineering. Dr. Saltzman’s honors and awards include: Camille and Henry Dreyfus Foundation Teacher-Scholar Award (1990); Allan C. Davis Medal as Maryland’s Outstanding Young Engineer (1995); the Controlled Release Society Young Investigator Award (1996); Fellow of the American Institute of Biological and Medical Engineers (1997); Professional Progress in Engineering Award from Iowa State University (2000); Britton Chance Distinguished Lecturer in Engineering and Medicine at the University of Pennsylvania (2000); Distinguished Lecturer of the Biomedical Engineering Society (2004); and Fellow of the Biomedical Engineering Society (2010).

ForSE 2010: the Forum for Social Entrepreneurs

Oct. 30th, 8am-6pm, Northeastern University West Village F & Behrakis Health Sciences Center

Net Impact is an international organization of social entrepreneurs, and we use business to solve social and environmental problems in a sustainable way.

This October 30th, we’re co-hosting (along with TiE Boston and NU’s Social Enterprise Institute) ForSE 2010: the Forum for Social Entrepreneurs. It’s an exciting event that’s bringing together expert panelists to discuss social enterprise in the spheres of health, education, technology, and sustainability. has all of the information that you’ll need to learn about:

* Panelists and panel descriptions
* How to enter Pitch SE, the social enterprise pitch contest
* Registration
* Logistics
* and more information!


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